Prethodno smo primijetili pojačane reakcije imunoglobulina A (IgA) u ekstremnom COVID-19, što bi moglo dati štetne rezultate. S obzirom na vitalnu funkciju IgA u imunološkim i upalnim odgovorima, namjera ovog ispitivanja bila je analizirati dinamički odgovor na promjenu izotipa IgA TGF-β1 u oboljelih od COVID-19.
Primijetili smo, u ukupno 153 oboljela od COVID-19, da su serumski rasponi TGF-β1 značajno povišeni u ranoj i središnjoj fazi COVID-19, te u korelaciji sa stupnjevima IgA specifičnim za SARS-CoV-2 , uz ocjenu APACHE-II kod oboljelih od ekstremne bolesti. S obzirom na genetsku povezanost aktivatora TGF-β1 THBS3 s ekstremnim COVID-19 prepoznatim u Inicijativi za genetiku domaćina COVID-19, ovo ispitivanje sugerira da bi TGF-β1 mogao imati ključnu funkciju u COVID-19.
Usporedne Procjena antigen pojedine anti-SARS-COV-2 antitijelo izotipa u COVID-19 stradalnika
Očekuje se da će serološki pregledi za otkrivanje anti-teškog akutnog respiratornog sindroma koronavirusa 2 (SARS-CoV-2) Abs u krvi utvrditi ljude koji su stekli imunitet na SARS-CoV-2 i naznaku seroprevalencije SARS-CoV-2 i infekcija.
Za otkrivanje Abs prema SARS-CoV-2 razvijeni su mnogi serološki pregledi . Unatoč tome, ovi ispiti imaju značajne varijacije u svojim specifičnostima i osjetljivosti, a o tome mogu li predvidjeti raspone neutraliziranja vježbi ili ne, tek će se odlučiti.
Ovo ispitivanje ima za cilj analizirati kinetiku i neutraliziranje vježbi različitih Ag-specifičnih izotipa Ab prema SARS-CoV-2 u serumu oboljelih od koronavirusa 2019 (COVID-19) potvrđenih PCR-om. Razvili smo testove mjerenja IgG, IgM i IgA za svaki Ag, zajedno s područjem vezanja receptora (RBD) šiljastog (S) proteina, S1 područjem, S proteinom pune dužine, S trimerom i nukleokapsidnim (N) područjem, na temelju uglavnom na ELISA -i.
Analize S proteina za sve izotipove potvrdile su prekomjernu specifičnost, dok su ispitivanja za sve izotipove prema N proteinu potvrdila smanjenje specifičnosti. Osjetljivost svih Ag izotipova Ab pouzdanih je vjerovala u vrijeme asortimana seruma, a svi su, osim IgM prema N proteinu, dosegli više od 90% na 15-21 dan nakon početka simptoma.
Najbolja korelacija s vježbom za neutraliziranje virusa otkrivena je za IgG prema RBD-u, a rasponi IgG-a prema RBD-u u serumima od 4 oboljela s ekstremnim COVID-19 povišeni sukladno s neutralizirajućom vježbom. Naši rezultati predstavljaju korisne informacije u vezi s odabirom seroloških pregleda. Pogledajte seroprevalenciju i analizu cjepiva.
Sastavi izotipa imunoglobulina za specifična protutijela ABO ovise o krvnoj grupi osobe i specifičnosti krvne grupe: Ishodi iz zdrave skupine donatora
Protutijela specifična za antigene ABO sustava krvne grupe od znanstvenog su značaja i imunološke znatiželje. Rutinske znanstvene strategije ponekad koriste strategije izravne ili kose hemaglutinacije za mjerenje IgM odnosno IgG.
Sada smo razvili jednostavnu tehniku s jednom epruvetom za kvantificiranje IgM, IgG i IgA posebno za antigene A i B s ciljem povećanja točnosti i ponovljivosti te za analizu odnosa između vrste antitijela ABO skupine i stadija protutijela.
Proučeni su uzorci plazme 300 dobrotvornih davatelja krvi. Raspon vezanja IgM i IgG na grimizne stanice reagensa skupine A i B mjeren je aglutinacijom (HA) i višebojnom citometrijom u pokretu (MC-FC). IgA je dodatno izmjeren pomoću MC-FC.
Otkriveno je da je naša FC tehnika znatno ekstra reproducibilnija od HA za mjerenje antitijela određenih krvnih grupa A i B. Otkrili smo statistički vitalne korelacije između antitijela izmjerenih pomoću GC-HA i MC-FC, međutim ima dosta varijacija koje ukazuju na to da ove strategije nisu jednake.
Pomoću MC-FC otkriveno je da rasponi IgM, IgG i IgA i izotopski profili ovise o svakoj donorskoj vrsti ABO i specifičnosti protutijela. Ovo ispitivanje pokazalo je heterogenost unutar profila klase imunoglobulina specifičnih antitijela ABO-krvne grupe unutar zdravih stanovnika.
Varijacije u profilima izotipa određenih antitijela ABO-krvne grupe mogle bi ukazati na osnovne varijacije unutar imunoloških mehanizama koji stvaraju ta antitijela. To je sklono povezivanju sa znanstvenim uvjetima gdje primjena ili prognoza mjesta ovise o otkrivanju i mjerenju antitijela specifičnih za ABO.
Novi sindrom izazvan supstitucijom aminokiseline E410 Okay unutar izotipa 3 neuronskog β-tubulina.
Missense mutacije u TUBB3, genu koji kodira neuronski specifični protein β-tubulin izotip 3, mogle bi uzrokovati udaljenu ili sindromsku kongenitalnu fibrozu ekstraokularnog mišićnog tkiva, vrstu kompliciranog kongenitalnog strabizma kojeg karakterizira pogrešno vođenje kranijalnog živca.
Jedna od mnogih osam mutacija TUBB3 za koje se izvješćuje da izazivaju kongenitalnu fibrozu ekstraokularnog mišićnog tkiva, c.1228G> A završava supstitucijom aminokiseline TUBB3 E410Okay koja odmah mijenja web mjesto vezanja na motor kinezin.
Izvještavamo detaljne fenotipove osam nepovezanih ljudi koji imaju ovu de novo mutaciju i tako ocrtavamo ‘sindrom TUBB3 E410Okay’. Ljudi koji su imali tu mutaciju prethodno su prijavljeni da imaju kongenitalnu fibrozu ekstraokularnog mišićnog tkiva, slabu točku lica, zaostajanje u razvoju i dostižnu perifernu neuropatiju.
Elektrofiziologijom sada potvrđujemo da se progresivna senzomotorna polineuropatija svakako odvaja s mutacijom te povećavamo fenotip TUBB3 E410Okay kako bi uključili Kallmannov sindrom (hipogonadotropni hipogonadizam i anosmiju), stereotipnu hipoplaziju srednje površine lica, mentalne poteškoće i, u nekim okolnostima, glasnu žicu. paraliza, traheomalacija i ciklično povraćanje.
Neuroslikavanje otkriva mršavo tjelešno tijelo i prednju komisuru, hipoplastično do odsutnih mirisnih brazdi, mirisnih žarulja i okulomotornih i facijalnih živaca, što pomaže temeljnim abnormalnostima u upravljanju aksonom i održavanju. Tako supstitucija E410Okay definira potpuno novu genetsku etiologiju za Moebiusov sindrom, Kallmannov sindrom i ciklično povraćanje.
Nadalje, c.1228G> Mutacija nije bila prisutna u DNK od oko 600 ljudi koji su imali i Kallmannov sindrom ili udaljeni ili sindromski poremećaj očne i/ili pokretljivosti lica, međutim koji nisu imali mješovite mogućnosti sindroma TUBB3 E410Okay, ističući specifičnost ove korelacije fenotip-genotip. Definicija sindroma TUBB3 E410Okay omogućit će kliničarima da utvrde oboljele osobe i predvide mutaciju uglavnom samo na temelju znanstvenih mogućnosti.
Nova tehnika za pročišćavanje polimeriziranog tubulina s materijalom s prekomjernim sadržajem acetiliranog izotipa .
Tubulin se može acetilirati/deacetilirati na Lys40 α-podjedinice. Istraživanje post-translacijske acetilacije/deacetilacije tubulina primjenom biokemijskih metoda zahtijevaju pripravke tubulina koji bi mogli biti obogaćeni AcTubulinom (acetiliranim tubulinom) i (radi usporedbe) pripravcima kojima nedostaje AcTubulin.
Biciklizam mikrotubula na sastanku i demontaži nudi pripravke tubulina koji sadrže malo ili nimalo AcTubulina. U okviru trenutnog ispitivanja pokazali smo da je ovaj rezultat posljedica prisutnosti prekomjerne vježbe deacetiliranja u ekstraktima.
Ovu vježbu deacetiliranja u homogenatima uma štakora inhibirali su TSA (trihostatin A) i tubacin, ali ne i nikotinamid, što ukazuje na to da se radi o HDAC6 (histon deacetilaza 6). TSA je potvrdio da nema utjecaja na polimerizaciju ili depolimerizaciju mikrotubula.
Koristili smo ta svojstva TSA-e za sprječavanje deacetilacije tijekom cijelog procesa montaže-demontaže. Učinkovito inhibicijsko fokusiranje TSA -e bilo je tri μM unutar homogenata i 1 μM unutar sljedećih koraka biciklizma. Usporedbom s imunološki pročišćenim AcTubulinom, procijenili smo da je ~ 64% molekula tubulina unutar tri ciklusirana pripravka acetilirano.
Armenian Hamster IgG Isotype control |
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| AIGGA-25 | ImmunoStep | 25 µg | EUR 339.55 |
Armenian Hamster IgG Isotype control |
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| AIGGB-200 | ImmunoStep | 200 µg | EUR 566.69 |
Armenian Hamster IgG Isotype control |
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| AIGGB-50 | ImmunoStep | 50 µg | EUR 287.14 |
Armenian Hamster IgG Isotype control |
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| AIGGF-200 | ImmunoStep | 200 µg | EUR 654.05 |
Armenian Hamster IgG Isotype control |
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| AIGGF-50 | ImmunoStep | 50 µg | EUR 322.08 |
Armenian Hamster IgG Isotype control |
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| AIGGPE-100 | ImmunoStep | 100 µg | EUR 619.1 |
Armenian Hamster IgG Isotype control |
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| AIGGPE-25 | ImmunoStep | 25 µg | EUR 304.61 |
Armenian Hamster IgG Isotype control |
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| AIGGPP-100 | ImmunoStep | 100 µg | EUR 688.99 |
Armenian Hamster IgG Isotype control |
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| AIGGPP-25 | ImmunoStep | 25 µg | EUR 322.08 |
Armenian Hamster IgG Isotype control |
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| AIGGPP5.5-100 | ImmunoStep | 100 µg | EUR 776.35 |
Armenian Hamster IgG Isotype control |
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| AIGGPP5.5-25 | ImmunoStep | 25 µg | EUR 339.55 |
Armenian Hamster IgG Isotype control |
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| AIGGPU-50 | ImmunoStep | 50 µg | EUR 234.72 |
Armenian Hamster IgG Isotype control |
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| AIGGPU-500 | ImmunoStep | 500 µg | EUR 514.27 |
Hamster (Syrian) IgG Isotype Control |
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| abx405032-025mg | Abbexa | 0.25 mg | EUR 460.8 |
PE Syrian Hamster IgG Isotype Control |
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| DL22376F-20Tests | DL Develop | 20Tests | EUR 158 |
PE Syrian Hamster IgG Isotype Control |
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| DL22376F-50Tests | DL Develop | 50Tests | EUR 233 |
PE Syrian Hamster IgG Isotype Control |
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| DL22391F-25ug | DL Develop | 25μg | EUR 137 |
PE Syrian Hamster IgG Isotype Control |
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| DL22391F-50ug | DL Develop | 50μg | EUR 182 |
Hamster (Armenian) IgG Isotype Control |
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| abx405028-025mg | Abbexa | 0.25 mg | EUR 460.8 |
Hamster (Arnenian) IgG Isotype Control |
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| abx405029-05mg | Abbexa | 0.5 mg | EUR 710.4 |
FITC Syrian Hamster IgG Isotype Control |
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| DL22375F-20Tests | DL Develop | 20Tests | EUR 158 |
FITC Syrian Hamster IgG Isotype Control |
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| DL22375F-50Tests | DL Develop | 50Tests | EUR 233 |
FITC Syrian Hamster IgG Isotype Control |
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| DL22390F-25ug | DL Develop | 25μg | EUR 137 |
FITC Syrian Hamster IgG Isotype Control |
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| DL22390F-50ug | DL Develop | 50μg | EUR 182 |
PE Armenian Hamster IgG Isotype Control |
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| DL22565F-20Tests | DL Develop | 20Tests | EUR 158 |
PE Armenian Hamster IgG Isotype Control |
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| DL22565F-50Tests | DL Develop | 50Tests | EUR 233 |
PE Armenian Hamster IgG Isotype Control |
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| DL22580F-25ug | DL Develop | 25μg | EUR 137 |
PE Armenian Hamster IgG Isotype Control |
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| DL22580F-50ug | DL Develop | 50μg | EUR 182 |
PE Armenian Hamster IgG Isotype Control |
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| E16FTCP006-025U | EnoGene | 25 μg | EUR 303.33 |
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Description: Available in various conjugation types. |
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PE Armenian Hamster IgG Isotype Control |
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| E16FTCP006-100U | EnoGene | 100 μg | EUR 693.33 |
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Description: Available in various conjugation types. |
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AF488 Syrian Hamster IgG Isotype Control |
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| DL22384F-20Tests | DL Develop | 20Tests | EUR 185 |
AF488 Syrian Hamster IgG Isotype Control |
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| DL22384F-50Tests | DL Develop | 50Tests | EUR 267.5 |
AF647 Syrian Hamster IgG Isotype Control |
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| DL22385F-20Tests | DL Develop | 20Tests | EUR 185 |
AF647 Syrian Hamster IgG Isotype Control |
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| DL22385F-50Tests | DL Develop | 50Tests | EUR 267.5 |
AF488 Syrian Hamster IgG Isotype Control |
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| DL22399F-25ug | DL Develop | 25μg | EUR 182 |
AF488 Syrian Hamster IgG Isotype Control |
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| DL22399F-50ug | DL Develop | 50μg | EUR 272 |
AF647 Syrian Hamster IgG Isotype Control |
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| DL22400F-25ug | DL Develop | 25μg | EUR 182 |
AF647 Syrian Hamster IgG Isotype Control |
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| DL22400F-50ug | DL Develop | 50μg | EUR 272 |
APC Armenian Hamster IgG Isotype Control |
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| DL22566F-20Tests | DL Develop | 20Tests | EUR 170 |
APC Armenian Hamster IgG Isotype Control |
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| DL22566F-50Tests | DL Develop | 50Tests | EUR 245 |
APC Armenian Hamster IgG Isotype Control |
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| DL22581F-25ug | DL Develop | 25μg | EUR 147.5 |
APC Armenian Hamster IgG Isotype Control |
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| DL22581F-50ug | DL Develop | 50μg | EUR 197 |
APC Armenian Hamster IgG Isotype Control |
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| E16FTCA006-025U | EnoGene | 25 μg | EUR 346.67 |
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Description: Available in various conjugation types. |
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APC Armenian Hamster IgG Isotype Control |
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| E16FTCA006-100U | EnoGene | 100 μg | EUR 780 |
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Description: Available in various conjugation types. |
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Biotin Syrian Hamster IgG Isotype Control |
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| DL22389F-25ug | DL Develop | 25μg | EUR 137 |
Biotin Syrian Hamster IgG Isotype Control |
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| DL22389F-50ug | DL Develop | 50μg | EUR 182 |
FITC Armenian Hamster IgG Isotype Control |
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| DL22564F-20Tests | DL Develop | 20Tests | EUR 158 |
FITC Armenian Hamster IgG Isotype Control |
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| DL22564F-50Tests | DL Develop | 50Tests | EUR 233 |
FITC Armenian Hamster IgG Isotype Control |
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| DL22579F-25ug | DL Develop | 25μg | EUR 137 |
FITC Armenian Hamster IgG Isotype Control |
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| DL22579F-50ug | DL Develop | 50μg | EUR 182 |
FITC Armenian Hamster IgG Isotype Control |
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| E16FTCF006-200U | EnoGene | 200 μg | EUR 736.67 |
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Description: Available in various conjugation types. |
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AF647 Armenian Hamster IgG Isotype Control |
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| DL22574F-20Tests | DL Develop | 20Tests | EUR 185 |
AF647 Armenian Hamster IgG Isotype Control |
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| DL22574F-50Tests | DL Develop | 50Tests | EUR 267.5 |
AF488 Armenian Hamster IgG Isotype Control |
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| DL22588F-25ug | DL Develop | 25μg | EUR 182 |
AF488 Armenian Hamster IgG Isotype Control |
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| DL22588F-50ug | DL Develop | 50μg | EUR 272 |
AF647 Armenian Hamster IgG Isotype Control |
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| DL22589F-25ug | DL Develop | 25μg | EUR 182 |
AF647 Armenian Hamster IgG Isotype Control |
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| DL22589F-50ug | DL Develop | 50μg | EUR 272 |
PerCP Armenian Hamster IgG Isotype Control |
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| E16FTCR006-025U | EnoGene | 25 μg | EUR 325 |
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Description: Available in various conjugation types. |
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PerCP Armenian Hamster IgG Isotype Control |
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| E16FTCR006-100U | EnoGene | 100 μg | EUR 780 |
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Description: Available in various conjugation types. |
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Biotin Armenian Hamster IgG Isotype Control |
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| DL22578F-25ug | DL Develop | 25μg | EUR 137 |
Biotin Armenian Hamster IgG Isotype Control |
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| DL22578F-50ug | DL Develop | 50μg | EUR 182 |
Biotin Armenian Hamster IgG Isotype Control |
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| E16FTCB006-200U | EnoGene | 200 μg | EUR 628.33 |
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Description: Available in various conjugation types. |
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Purified Armenian Hamster IgG Isotype Control |
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| DL22577F-25ug | DL Develop | 25μg | EUR 137 |
Purified Armenian Hamster IgG Isotype Control |
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| DL22577F-50ug | DL Develop | 50μg | EUR 182 |
Hamster (Syrian) IgG Isotype Control (FITC) |
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| abx405033-01mg | Abbexa | 0.1 mg | EUR 477.6 |
Hamster (Arnenian) IgG Isotype Control (RPE) |
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| abx405031-01mg | Abbexa | 0.1 mg | EUR 610.8 |
Hamster (Arnenian) IgG Isotype Control (FITC) |
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| abx405030-01mg | Abbexa | 0.1 mg | EUR 460.8 |
Hamster IgG, purified (Syrian, isotype control) |
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| 20003-1 | Alpha Diagnostics | 1 mg | EUR 169.2 |
PE-Cy5 Armenian Hamster IgG Isotype Control |
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| E16FTCC006-025U | EnoGene | 25 μg | EUR 346.67 |
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Description: Available in various conjugation types. |
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PE-Cy5 Armenian Hamster IgG Isotype Control |
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| E16FTCC006-100U | EnoGene | 100 μg | EUR 780 |
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Description: Available in various conjugation types. |
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PE-Cy7 Armenian Hamster IgG Isotype Control |
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| E16FTCN006-025U | EnoGene | 25 μg | EUR 346.67 |
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Description: Available in various conjugation types. |
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PE-Cy7 Armenian Hamster IgG Isotype Control |
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| E16FTCN006-100U | EnoGene | 100 μg | EUR 650 |
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Description: Available in various conjugation types. |
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APC-Cy7 Armenian Hamster IgG Isotype Control |
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| E16FTCO006-025U | EnoGene | 25 μg | EUR 390 |
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Description: Available in various conjugation types. |
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Hamster IgG, purified (Armenian, Isotype control) |
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| 20003-1AH | Alpha Diagnostics | 1 mg | EUR 315.6 |
PE/Cyanine7 Armenian Hamster IgG Isotype Control |
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| DL22569F-20Tests | DL Develop | 20Tests | EUR 185 |
PE/Cyanine7 Armenian Hamster IgG Isotype Control |
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| DL22569F-50Tests | DL Develop | 50Tests | EUR 267.5 |
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22570F-20Tests | DL Develop | 20Tests | EUR 185 |
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22570F-50Tests | DL Develop | 50Tests | EUR 267.5 |
PE/Cyanine7 Armenian Hamster IgG Isotype Control |
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| DL22584F-25ug | DL Develop | 25μg | EUR 182 |
PE/Cyanine7 Armenian Hamster IgG Isotype Control |
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| DL22584F-50ug | DL Develop | 50μg | EUR 272 |
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22585F-25ug | DL Develop | 25μg | EUR 182 |
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22585F-50ug | DL Develop | 50μg | EUR 272 |
PerCP-Cy5.5 Armenian Hamster IgG Isotype Control |
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| E16FTCS006-100U | EnoGene | 100 μg | EUR 888.33 |
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Description: Available in various conjugation types. |
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NE Purified Armenian Hamster IgG Isotype Control |
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| E16FTCY006-050U | EnoGene | 50 μg | EUR 260 |
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Description: Available in various conjugation types. |
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NE Purified Armenian Hamster IgG Isotype Control |
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| E16FTCY006-1000U | EnoGene | 1 mg | EUR 1516.67 |
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Description: Available in various conjugation types. |
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NE Purified Armenian Hamster IgG Isotype Control |
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| E16FTCY006-500U | EnoGene | 500 μg | EUR 823.33 |
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Description: Available in various conjugation types. |
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Syrian Hamster IgG Isotype Control(APC Conjugated) |
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| DL22377F-20Tests | DL Develop | 20 Tests | EUR 120 |
Syrian Hamster IgG Isotype Control(APC Conjugated) |
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| DL22377F-50Tests | DL Develop | 50 Tests | EUR 210 |
UNE Purified Armenian Hamster IgG Isotype Control |
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| E16FTCZ006-1000U | EnoGene | 1 mg | EUR 1581.67 |
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Description: Available in various conjugation types. |
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UNE Purified Armenian Hamster IgG Isotype Control |
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| E16FTCZ006-100U | EnoGene | 100 μg | EUR 433.33 |
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Description: Available in various conjugation types. |
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Syrian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22378F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22378F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22393F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22393F-50ug | DL Develop | 50 μg | EUR 264 |
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22571F-20Tests | DL Develop | 20Tests | EUR 185 |
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22571F-50Tests | DL Develop | 50Tests | EUR 267.5 |
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22586F-25ug | DL Develop | 25μg | EUR 182 |
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control |
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| DL22586F-50ug | DL Develop | 50μg | EUR 272 |
AF/LE Purified Syrian Hamster IgG Isotype Control |
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| DL22387F-25ug | DL Develop | 25μg | EUR 137 |
AF/LE Purified Syrian Hamster IgG Isotype Control |
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| DL22387F-50ug | DL Develop | 50μg | EUR 182 |
Armenian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22567F-20Tests | DL Develop | 20 Tests | EUR 150 |
Armenian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22567F-50Tests | DL Develop | 50 Tests | EUR 255 |
Armenian Hamster IgG Isotype Control(AF488 Conjugated) |
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| DL22573F-20Tests | DL Develop | 20 Tests | EUR 150 |
Armenian Hamster IgG Isotype Control(AF488 Conjugated) |
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| DL22573F-50Tests | DL Develop | 50 Tests | EUR 255 |
Armenian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22582F-25ug | DL Develop | 25 μg | EUR 144 |
Armenian Hamster IgG Isotype Control(PerCP Conjugated) |
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| DL22582F-50ug | DL Develop | 50 μg | EUR 264 |
AF/LE Purified Armenian Hamster IgG Isotype Control |
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| DL22576F-25ug | DL Develop | 25μg | EUR 137 |
AF/LE Purified Armenian Hamster IgG Isotype Control |
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| DL22576F-50ug | DL Develop | 50μg | EUR 182 |
Alexa Fluor® 488 Arm. Hamster IgG Isotype Control |
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| E16FTCG006-100U | EnoGene | 100 μg | EUR 658.67 |
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Description: Available in various conjugation types. |
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Alexa Fluor® 647 Arm. Hamster IgG Isotype Control |
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| E16FTCK006-100U | EnoGene | 100 μg | EUR 650 |
|
Description: Available in various conjugation types. |
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Hamster IgG-Cy5 conjugate, isotype control (Syrian) |
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| 20003-1-Cy5 | Alpha Diagnostics | 50 tests | EUR 270 |
Hamster IgG-HRP conjugate, isotype control (Syrian) |
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| 20003-1-HP | Alpha Diagnostics | 100 tests | EUR 196.8 |
Armenian Hamster IgG Isotype Control (PIP), APC-100ug |
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| QAB69-APC-100ug | EnQuireBio | 100ug | EUR 351.6 |
Hamster IgG-FITC conjugate, isotype control (Syrian) |
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| 20003-1-F | Alpha Diagnostics | 100 tests | EUR 196.8 |
Hamster IgG-Biotin conjugate, isotype control (Syrian) |
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| 20003-1-B | Alpha Diagnostics | 100 test | EUR 196.8 |
Alexa Fluor® 700 Armenian Hamster IgG Isotype Control |
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| E16FTCI006-100U | EnoGene | 100 μg | EUR 650 |
|
Description: Available in various conjugation types. |
|||
Syrian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22379F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22379F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(PE/Cyanine7 Conjugated) |
|||
| DL22380F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(PE/Cyanine7 Conjugated) |
|||
| DL22380F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5.5 Conjugated) |
|||
| DL22381F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5.5 Conjugated) |
|||
| DL22381F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22394F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22394F-50ug | DL Develop | 50 μg | EUR 264 |
Syrian Hamster IgG Isotype Control(PE/Cyanine7 Conjugated) |
|||
| DL22395F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(PE/Cyanine7 Conjugated) |
|||
| DL22395F-50ug | DL Develop | 50 μg | EUR 264 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5.5 Conjugated) |
|||
| DL22396F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(PE/Cyanine5.5 Conjugated) |
|||
| DL22396F-50ug | DL Develop | 50 μg | EUR 264 |
Syrian Hamster IgG Isotype Control(APC/Cyanine5.5 Conjugated) |
|||
| DL22383F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(APC/Cyanine5.5 Conjugated) |
|||
| DL22383F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(APC/Cyanine7 Conjugated) |
|||
| DL22386F-20Tests | DL Develop | 20 Tests | EUR 150 |
Syrian Hamster IgG Isotype Control(APC/Cyanine7 Conjugated) |
|||
| DL22386F-50Tests | DL Develop | 50 Tests | EUR 255 |
Syrian Hamster IgG Isotype Control(APC/Cyanine5.5 Conjugated) |
|||
| DL22398F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(APC/Cyanine5.5 Conjugated) |
|||
| DL22398F-50ug | DL Develop | 50 μg | EUR 264 |
Syrian Hamster IgG Isotype Control(APC/Cyanine7 Conjugated) |
|||
| DL22401F-25ug | DL Develop | 25 μg | EUR 144 |
Syrian Hamster IgG Isotype Control(APC/Cyanine7 Conjugated) |
|||
| DL22401F-50ug | DL Develop | 50 μg | EUR 264 |
Hamster IgG-R-PE conjugate, isotype control (Syrian) |
|||
| 20003-1-PE | Alpha Diagnostics | 50 tests | EUR 270 |
Armenian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22568F-20Tests | DL Develop | 20 Tests | EUR 150 |
Armenian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22568F-50Tests | DL Develop | 50 Tests | EUR 255 |
Armenian Hamster IgG Isotype Control(PE/Cyanine5 Conjugated) |
|||
| DL22583F-25ug | DL Develop | 25 μg | EUR 144 |
Proteinski profili tih preparata tubulina, prema procjeni pomoću SDS/PAGE i Coomassie Blue bojenja, slični su profilima pripravka koji potpuno nedostaje AcTubulin dobiven ciklusima montaže-demontaže u odsutnosti TSA. Stanje tirozacije i kinetika montaže-demontaže in vitro bili su identični bez obzira na diplomu acetilacije.
