Karakterizacija antitijela ključna je za razumijevanje imunološkog sustava i poboljšanje dijagnostike i terapije. Sadašnje primijenjene znanosti prvenstveno su specijalizirane za otkrivanje antigen-specifičnog imunoglobulina G (IgG) primjenom skupnih mjerenja u jednom kompleksu, kojima nedostaju podaci o različitim izotipovima i specifičnostima antitijela određene osobe.
Digitalni imunološki testovi koji se uglavnom temelje na amplifikaciji nukleinskih kiselina pokazali su vrhunsku učinkovitost dopuštajući detekciju pojedinačnih molekula u multipleks i osjetljivoj metodi. Na ovom istraživanju pokazat ćemo po prvi put test amplifikacije imuno-valjanja kruga (imuno-RCA) za multipleksnu detekciju tri izotipa specifičnih antitijela antitela (IgG, IgA i IgM) i njegovu integraciju s mikrograviranjem.
Da bismo potvrdili ovu metodu, koristili smo autoimunu bolest imunološki posredovanu trombotičku trombocitopeničnu purpuru (iTTP) jer je bolest manekenke s anti-ADAMTS13 autoantitijelima dijagnosticirana kao cilj molekula. Za uspostavu izotipova auto-antitijela anti-ADAMTS13, osmislili smo skup od tri različita konjugata antitijelo-oligonukleotid za identifikaciju i naknadnu amplifikaciju i vizualizaciju putem RCA.
Kako bismo potvrdili ovu metodu, prvo smo potvrdili specifičnost testa od> 88% i nisku granicu detekcije od 0. tri ng/mL unutar šiljastog pufera. Nakon toga smo proveli prikupljanje razrjeđenja uzorka iTTP plazme za multipleksnu detekciju tri izotipa s većom osjetljivošću u usporedbi s enzimskim imunosorbentom.
Na kraju, pokazali smo jednostaničnu evaluaciju ljudskih B stanica i hibridomskih stanica za detekciju izlučenih antitijela pomoću mikrograviranja i postigli otkrivanje 23. tri pg/mL protutijela izlučenih na sat. Ova metoda može pomoći u boljem razumijevanju distribucije izotipa antitijela i njihove uloge u brojnim bolestima.
Serum IGM teškim lancem pot izotipovi i lagani lanac varijante objavio u velikom škarpine (Epinephelus lanceolatus) kroz pročišćavanje proteina afinitet, masene spektrometrije i genoma sekvenciranje
Dva podizotipa teškog (H) lanca IgM (80 i 40 kDa) i dvije blage (L) varijante lanca (25 i 30 kDa) otkrivena su u serumu velike škarpine (Epinephelus lanceolatus), pročišćene taloženjem amonijevog sulfata afinitetnom kromatografijom na proteinu A.
Ova metodologija dala je 5,24 mg/mL IgM prekomjerne čistoće iz seruma kirnje, s učinkovitošću procijenjenom na 39,5% obnavljanja iz sirovog seruma. H i L lanci su prepoznati pomoću SDS-PAGE i masene spektrometrije (MS). Nanopore dugo čitanje sekvenciranja korišteno je za generiranje genomskog kontiga (MW768935), koji sadrži Cμ, Cδ lokuse, V H područja i H lanac Postajući član faze.
cDNA sekvenciranje Cμ transkripata (MW768933 i MW768934) korišteno je za osvjetljavanje genomskog kontiga i odlučivanje o egzonima i intronima odgovarajućeg lokusa. Mapiranje MS peptida otkrilo je da se 80 kDa H lanac sastoji od C H HL i V L gena. Puzotivni IgM podizotipi dodatno su prijavljeni u Epinephelus itajara i Epinephelus coioides. Prisutnost IgM podizotipa također bi mogla biti očuvana osobina među vrstama epinefelusa.
Tubulin- izotip ocjenjivanja dviju vrsta trava otpornih na dinitroanilin herbicide.
Biotipovi otporni na trifluralin Eleusine indica (L.) Gaertn. (guščja trava) i Setaria viridis (L.) Beauv. (neiskusni lisičji rep) pokazuju unakrsnu rezistenciju na različite dinitroanilin herbicide. Budući da se o mikrotubulama razmišlja o prvom ciljnom mjestu za dinitroanilin herbicide, istraživali smo je li razlika u osjetljivosti rezistentnih i ranjivih biotipova tih vrsta na modificirane tubulinske polipeptide.
Jednodimenzionalna i dvodimenzionalna elektroforeza od poliakrilamidnog gela pomiješana s imunoblotingom korištenjem dobro karakteriziranih anti-tubulinskih monoklonskih protutijela korištena je za pokazivanje domaćinstva izotipa tubulina u svakoj vrsti.
Sadnice E. indica pokazale su 4 izotipa β-tubulina i jedan izotip α-tubulina, dok su biljke S. viridis pokazale dva izotipa β-tubulina i dva α-tubulina. Usporedba osjetljivih i rezistentnih biotipova unutar svake vrste nije pokazala varijacije u elektroforetskim svojstvima brojnih izotipova tubulina. Ovi ishodi ne predstavljaju dokaz da je rezistencija na dinitroanilin herbicide povezana s modificiranim polipeptidom tubulina u ovim biotipima E. indica ili S. viridis.
Brojni izotipi aktina u usjevima : brojni geni za brojne uloge?
Biljni aktini kodirani su genskim domaćinstvom. Bez obzira na bitan značaj citoskeleta aktina za izgradnju i performanse biljaka, značaj izotipova aktina određene osobe i njihove posebne uloge u brojnim biljnim tkivima, pa čak i pojedinačnim stanicama relativno je slabo shvaćen.
Ova evaluacija sažima naše sadašnje informacije o kućanstvu gena biljnog aktina zajedno s njegovom evolucijom, izgradnjom gena i proteina te profilima ekspresije i regulacijom. Prvenstveno na temelju ovih pozadinskih podataka, evaluiramo analize mutanata i komplementarne analize u Arabidopsisu kako bismo privukli sve veću sliku preklapanja i posebnih uloga izotipova biljnih aktina. Na kraju, proučavamo hipoteze koje objašnjavaju mehanizme sposobnosti specifičnih za izotip.
Spektri vezanja izotipova šarana C3 nasuprot čistim ciljevima nepristrani su zbog specifičnosti vezanja njihovog tioestra.
Središnji element komplementa, C3, ima fleksibilan položaj u urođenoj imunološkoj zaštiti kralježnjaka i nekoliko beskralježnjaka. Značajan molekularni atribut ovog elementa je tioesterska web stranica unutar lanca koja omogućuje da se C3 kovalentno veže za svoj cilj.
Izviješteno je da se želja vezanja tioestera za hidroksilne ili amino timove prvenstveno ocrtava prisutnošću ili odsutnošću katalitičkog histidinskog ostatka na mjestu 1126 u ljudskom C3. U teleost-ovima je otkriven roman C3 (koji nije Njegova vrsta), zajedno s raširenom Njegovom vrstom C3. Ove različite izoforme C3 mogle bi predstavljati raznolikost unutar vezanja cilja koje se može pripisati potpuno različitim specifičnostima vezanja njihovih tioestera.
U okviru sadašnjeg istraživanja proučavamo pretpostavljenu povezanost katalitičkog histidina sa spektrom vezanja dva glavna C3 izotipa šarana u smjeru brojnih lutaka i čistih meta. Ishodi otkrivaju da ne-His vrsta C3, relativno nego njegova vrsta C3, ima širi raspon veznog spektra, bez obzira na to što je specifičnost vezanja njegovog tioestra ograničena na amino timove.
Poslije se pretpostavlja da spektri vezanja izotipova C3 obično nisu ocrtani specifičnošću vezanja tioestera, ali na njih dodatno utječu varijacije u molekularnim uzorcima povezanim s mikrobima koji aktiviraju komplement. Općenito, trenutne informacije ukazuju na to da ne-His vrsta C3 ima veliki položaj u odnosu na bakterijske infekcije u sustavu zaštite riba.
Ekspresija izotipova glutation-s-transferaze u odnosu na osjetljivost na doksorubicin i prognozu u bolesnika s bubrežnim karcinomom.
Uzorci su dobiveni iz tumora i susjednog bubrega u 29 oboljelih od bubrežnog karcinoma. Ekspresija alfa, pi i mu izoformi glutation-S-transferaze (GST) procijenjena je u formalinom pričvršćenim parafinskim dijelovima konvencionalnog i neoplastičnog bubrega, nakon objavljivanja odgovarajućih poliklonskih protutijela. čije je vezivanje prepoznato pristupom kosoj peroksidazi.
Mouse IgG3 Isotype Control (PerCP) |
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| abx200591-100ug | Abbexa | 100 ug | EUR 878.4 |
Mouse IgG3 Isotype Control Purified |
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| 11-459-C025 | ExBio | 0.025 mg | EUR 105.6 |
Mouse IgG3 Isotype Control Purified |
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| 11-459-C100 | ExBio | 0.1 mg | EUR 163.2 |
Mouse IgG3 isotype control, purified |
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| 20102-104 | Alpha Diagnostics | 100 ug | EUR 169.2 |
PE mouse IgG3, κ Isotype Control |
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| E16FMCP005K-025U | EnoGene | 25 μg | EUR 411.67 |
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Description: Available in various conjugation types. |
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FITC mouse IgG3, κ Isotype Control |
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| E16FMCF005K-050U | EnoGene | 50 μg | EUR 325 |
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Description: Available in various conjugation types. |
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Mouse IgG3 Isotype Control (OC-515) |
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| abx200593-100ug | Abbexa | 100 ug | EUR 727.2 |
Mouse IgG3 Isotype Control (CF-Blue) |
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| abx200592-100ug | Abbexa | 100 ug | EUR 577.2 |
Biotin mouse IgG3, κ Isotype Control |
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| E16FMCB005K-050U | EnoGene | 50 μg | EUR 260 |
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Description: Available in various conjugation types. |
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Purified mouse IgG3, κ Isotype Control |
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| E16FMCK005K-050U | EnoGene | 50 μg | EUR 411.67 |
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Description: Available in various conjugation types. |
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Mouse IgG3-PE conjugate (isotype control) |
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| 20102-104-PE | Alpha Diagnostics | 50 Tests | EUR 242.4 |
Mouse IgG3-HRP conjugate (isotype control) |
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| 20102-104-HP | Alpha Diagnostics | 50 Tests | EUR 196.8 |
Mouse IgG3-FITC conjugate (isotype control) |
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| 20102-104-F | Alpha Diagnostics | 50 tests | EUR 196.8 |
NE Purified mouse IgG3, κ Isotype Control |
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| E16FMCY005K-500U | EnoGene | 500 μg | EUR 780 |
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Description: Available in various conjugation types. |
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Mouse IgG3-Biotin conjugate (isotype control) |
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| 20102-104-B | Alpha Diagnostics | 50 Tests | EUR 196.8 |
Mouse IgG3 Isotype control (purified) validated fo |
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| NG908 | Innovex | 7 ml | EUR 245 |
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Description: Mouse IgG3 Isotype control (purified) validated for IHC; Ready-To-Use |
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Mouse IgG3 Isotype control (purified) validated fo |
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| NG908C | Innovex | 1 ml | EUR 285 |
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Description: Mouse IgG3 Isotype control (purified) validated for IHC; Concentrate |
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Mouse IgG3-PE-Cy5 conjugate (isotype control) |
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| 20102-104-PC5 | Alpha Diagnostics | 50 Tests | EUR 270 |
Alexa Fluor® 488 mouse IgG3, κ Isotype Control |
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| E16FMCG005K-100U | EnoGene | 100 μg | EUR 845 |
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Description: Available in various conjugation types. |
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Alexa Fluor® 647 mouse IgG3, κ Isotype Control |
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| E16FMCK005K-025U | EnoGene | 25 μg | EUR 173.33 |
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Description: Available in various conjugation types. |
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Mouse IgG3 Isotype Control DyLight® 488 |
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| L4-459-C100 | ExBio | 0.1 mg | EUR 255.6 |
Mouse IgG3 Isotype Control DyLight® 650 |
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| L6-459-C100 | ExBio | 0.1 mg | EUR 255.6 |
Mouse IgG1 Isotype Control |
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| abx139001-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG1 Isotype Control |
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| abx139002-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG1 Isotype Control |
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| abx139008-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG1 Isotype Control |
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| abx200564-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG1 Isotype Control |
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| abx405007-01mg | Abbexa | 0.1 mg | EUR 493.2 |
Mouse IgG1 Isotype Control |
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| abx405009-05mg | Abbexa | 0.5 mg | EUR 828 |
Mouse IgG1 Isotype Control |
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| abx405012-1mg | Abbexa | 1 mg | EUR 1296 |
Mouse IgG1 Isotype Control |
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| abx405064-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG1 Isotype Control |
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| abx405067-05mg | Abbexa | 0.5 mg | EUR 994.8 |
Mouse IgG1 Isotype Control |
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| E2790003 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Mouse IgG2a Isotype Control |
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| abx139004-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG2a Isotype Control |
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| abx139005-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG2b Isotype Control |
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| abx139006-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG2a Isotype Control |
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| abx139009-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG2b Isotype Control |
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| abx139011-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Mouse IgG2a Isotype Control |
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| abx200572-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG2b Isotype Control |
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| abx200580-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG2a Isotype Control |
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| abx405013-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG2a Isotype Control |
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| abx405015-05mg | Abbexa | 0.5 mg | EUR 828 |
Mouse IgG2a Isotype Control |
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| abx405018-1mg | Abbexa | 1 mg | EUR 1328.4 |
Mouse IgG2b Isotype Control |
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| abx405056-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG2b Isotype Control |
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| abx405061-1mg | Abbexa | 1 mg | EUR 1296 |
Mouse IgG2a Isotype Control |
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| abx405070-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG2a Isotype Control |
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| abx405073-05mg | Abbexa | 0.5 mg | EUR 994.8 |
Mouse IgG2a Isotype Control |
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| 10R-I117d | Fitzgerald | 1 mg | EUR 663.6 |
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Description: Purified Mouse IgG2a Isotype Control |
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Mouse IgG2a Isotype Control |
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| E2790004 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Mouse IgG2b Isotype Control |
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| E2790005 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Mouse IgG Isotype Control |
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| IC002-100ul | SAB | 100ul | EUR 146.4 |
Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 PE |
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| IMSIGG3KICA1123CPE100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 PE |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 PE |
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| IMSIGG3KICA1123CPE25UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 PE |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 APC |
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| IMSIGG3KICA1123CAPC100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 APC |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 APC |
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| IMSIGG3KICA1123CAPC25UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 APC |
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Mouse IgG1 Isotype Control (PE) |
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| abx139025-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG1 Isotype Control (PE) |
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| abx200566-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG1 Isotype Control PE |
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| 1P-632-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG1 Isotype Control PE |
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| 1P-632-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG1 Isotype Control (PE) |
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| E2790238 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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PE mouse IgG1 Isotype Control |
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| E16FMCP001-050 | EnoGene | 50 tests | EUR 235.2 |
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Description: Available in various conjugation types. |
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PE mouse IgG1 Isotype Control |
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| E16FMCP001-100 | EnoGene | 100 Tests | EUR 336 |
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Description: Available in various conjugation types. |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 FITC |
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| IMSIGG3KICA1123CFITC100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 FITC |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 FITC |
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| IMSIGG3KICA1123CFITC25UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 FITC |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF488 |
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| IMSIGG3KICA1123CAF488100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF488 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF488 |
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| IMSIGG3KICA1123CAF48825UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF488 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF647 |
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| IMSIGG3KICA1123CAF647100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF647 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF647 |
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| IMSIGG3KICA1123CAF64725UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 AF647 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 ER780 |
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| IMSIGG3KICA1123CER780100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 ER780 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 ER780 |
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| IMSIGG3KICA1123CER78025UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 ER780 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 EV450 |
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| IMSIGG3KICA1123CEV450100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 EV450 |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 EV450 |
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| IMSIGG3KICA1123CEV45025UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 EV450 |
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Mouse IgG1 Isotype Control (APC) |
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| abx139022-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG1 Isotype Control (APC) |
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| abx200567-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG1 Isotype Control (RPE) |
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| abx405011-100tests | Abbexa | 100 tests | EUR 760.8 |
Mouse IgG1 Isotype Control (APC) |
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| abx405065-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG1 Isotype Control (RPE) |
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| abx405069-100tests | Abbexa | 100 tests | EUR 560.4 |
Mouse IgG1 Isotype Control APC |
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| 1A-632-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG1 Isotype Control APC |
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| 1A-632-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG1 Isotype Control (APC) |
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| E2790221 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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APC mouse IgG1 Isotype Control |
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| E16FMCA001-050 | EnoGene | 50 tests | EUR 268.67 |
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Description: Available in various conjugation types. |
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APC mouse IgG1 Isotype Control |
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| E16FMCA001-100 | EnoGene | 100 Tests | EUR 403.2 |
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Description: Available in various conjugation types. |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 Biotin |
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| IMSIGG3KICA1123CBL100UG | Innovative research | each | EUR 150 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 Biotin |
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Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 Biotin |
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| IMSIGG3KICA1123CBL25UG | Innovative research | each | EUR 55 |
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Description: Mouse IgG3 Kappa Isotype Control Monoclonal Clone A1123 Biotin |
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Mouse IgG1 Isotype Control (FITC) |
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| abx139024-01mg | Abbexa | 0.1 mg | EUR 460.8 |
Mouse IgG1 Isotype Control (FITC) |
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| abx200565-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG1 Isotype Control (FITC) |
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| abx405010-01mg | Abbexa | 0.1 mg | EUR 610.8 |
Mouse IgG1 Isotype Control (FITC) |
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| abx405068-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG1 Isotype Control FITC |
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| 1F-632-C025 | ExBio | 0.025 mg | EUR 129.6 |
Mouse IgG1 Isotype Control FITC |
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| 1F-632-C100 | ExBio | 0.1 mg | EUR 212.4 |
Mouse IgG1 Isotype Control (FITC) |
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| E2790234 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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FITC mouse IgG1 Isotype Control |
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| E16FMCF001-050 | EnoGene | 50 tests | EUR 168 |
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Description: Available in various conjugation types. |
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FITC mouse IgG1 Isotype Control |
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| E16FMCF001-100 | EnoGene | 100 Tests | EUR 268.8 |
|
Description: Available in various conjugation types. |
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Mouse IgG1 Isotype Control (PerCP) |
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| abx139026-01mg | Abbexa | 0.1 mg | EUR 560.4 |
Mouse IgG1 Isotype Control (PerCP) |
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| abx200568-100ug | Abbexa | 100 ug | EUR 510 |
Mouse IgG1 Isotype Control PerCP |
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| PC-632-C025 | ExBio | 0.025 mg | EUR 163.2 |
Mouse IgG1 Isotype Control PerCP |
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| PC-632-C100 | ExBio | 0.1 mg | EUR 277.2 |
Mouse IgG2a Isotype Control (PE) |
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| abx139015-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG2b Isotype Control (PE) |
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| abx139020-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG2a Isotype Control (PE) |
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| abx200574-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG2b Isotype Control (PE) |
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| abx200582-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG2b Isotype Control PE |
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| 1P-692-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG2b Isotype Control PE |
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| 1P-692-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG2a Isotype Control PE |
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| 1P-724-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG2a Isotype Control PE |
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| 1P-724-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG2a Isotype Control (PE) |
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| E2790239 | EnoGene | 100ul | EUR 225 |
|
Description: Available in various conjugation types. |
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Mouse IgG2b Isotype Control (PE) |
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| E2790240 | EnoGene | 100ul | EUR 225 |
|
Description: Available in various conjugation types. |
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PE mouse IgG2a Isotype Control |
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| E16FMCP002-050 | EnoGene | 50 tests | EUR 235.2 |
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Description: Available in various conjugation types. |
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PE mouse IgG2a Isotype Control |
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| E16FMCP002-100 | EnoGene | 100 Tests | EUR 336 |
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Description: Available in various conjugation types. |
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PE mouse IgG2b Isotype Control |
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| E16FMCP003-050 | EnoGene | 50 tests | EUR 235.2 |
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Description: Available in various conjugation types. |
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PE mouse IgG2b Isotype Control |
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| E16FMCP003-100 | EnoGene | 100 Tests | EUR 336 |
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Description: Available in various conjugation types. |
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Mouse IgG1 Isotype Control (Biotin) |
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| abx139023-01mg | Abbexa | 0.1 mg | EUR 460.8 |
Mouse IgG1 Isotype Control (Biotin) |
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| abx405008-01mg | Abbexa | 0.1 mg | EUR 610.8 |
Mouse IgG1 Isotype Control (Biotin) |
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| abx405066-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG1 Isotype Control Biotin |
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| 1B-632-C025 | ExBio | 0.025 mg | EUR 129.6 |
Mouse IgG1 Isotype Control Biotin |
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| 1B-632-C100 | ExBio | 0.1 mg | EUR 212.4 |
Biotin mouse IgG1 Isotype Control |
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| E16FMCB001-050 | EnoGene | 50 tests | EUR 168 |
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Description: Available in various conjugation types. |
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Biotin mouse IgG1 Isotype Control |
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| E16FMCB001-100 | EnoGene | 100 Tests | EUR 268.8 |
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Description: Available in various conjugation types. |
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Biotin mouse IgG1 Isotype Control |
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| E16FMCB001-100U | EnoGene | 100 μg | EUR 268.8 |
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Description: Available in various conjugation types. |
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Biotin mouse IgG1 Isotype Control |
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| E16FMCB001-500U | EnoGene | 500 μg | EUR 739.2 |
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Description: Available in various conjugation types. |
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Mouse IgG2a Isotype Control (APC) |
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| abx139012-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG2b Isotype Control (APC) |
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| abx139017-01mg | Abbexa | 0.1 mg | EUR 510 |
Mouse IgG2a Isotype Control (APC) |
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| abx200575-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG2b Isotype Control (APC) |
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| abx200583-50ug | Abbexa | 50 ug | EUR 510 |
Mouse IgG2a Isotype Control (RPE) |
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| abx405017-100tests | Abbexa | 100 tests | EUR 760.8 |
Mouse IgG2b Isotype Control (APC) |
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| abx405057-100tests | Abbexa | 100 tests | EUR 577.2 |
Mouse IgG2b Isotype Control (RPE) |
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| abx405060-100tests | Abbexa | 100 tests | EUR 560.4 |
Mouse IgG2a Isotype Control (APC) |
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| abx405071-100tests | Abbexa | 100 tests | EUR 510 |
Mouse IgG2a Isotype Control (RPE) |
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| abx405075-100tests | Abbexa | 100 tests | EUR 560.4 |
Mouse IgG2b Isotype Control APC |
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| 1A-692-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG2b Isotype Control APC |
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| 1A-692-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG2a Isotype Control APC |
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| 1A-724-C025 | ExBio | 0.025 mg | EUR 146.4 |
Mouse IgG2a Isotype Control APC |
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| 1A-724-C100 | ExBio | 0.1 mg | EUR 244.8 |
Mouse IgG1 FITC (isotype control) |
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| MG1F-100 | Alpha Diagnostics | 100 Tests | EUR 489.6 |
Mouse IgG1 FITC (isotype control) |
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| MG1F-25 | Alpha Diagnostics | 25 Tests | EUR 270 |
Mouse IgG2a Isotype Control (APC) |
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| E2790222 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Mouse IgG2b Isotype Control (APC) |
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| E2790223 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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APC mouse IgG2a Isotype Control |
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| E16FMCA002-050 | EnoGene | 50 tests | EUR 268.8 |
|
Description: Available in various conjugation types. |
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APC mouse IgG2a Isotype Control |
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| E16FMCA002-100 | EnoGene | 100 Tests | EUR 403.2 |
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Description: Available in various conjugation types. |
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APC mouse IgG2b Isotype Control |
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| E16FMCA003-050 | EnoGene | 50 tests | EUR 268.8 |
|
Description: Available in various conjugation types. |
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APC mouse IgG2b Isotype Control |
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| E16FMCA003-100 | EnoGene | 100 Tests | EUR 403.2 |
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Description: Available in various conjugation types. |
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Mouse IgG2a Isotype Control (FITC) |
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| abx139014-01mg | Abbexa | 0.1 mg | EUR 460.8 |
Mouse IgG2b Isotype Control (FITC) |
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| abx139019-01mg | Abbexa | 0.1 mg | EUR 460.8 |
Mouse IgG2a Isotype Control (FITC) |
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| abx200573-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG2b Isotype Control (FITC) |
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| abx200581-100ug | Abbexa | 100 ug | EUR 376.8 |
Mouse IgG2a Isotype Control (FITC) |
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| abx405016-01mg | Abbexa | 0.1 mg | EUR 610.8 |
Mouse IgG2b Isotype Control (FITC) |
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| abx405059-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG2a Isotype Control (FITC) |
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| abx405074-100tests | Abbexa | 100 tests | EUR 493.2 |
Mouse IgG2b Isotype Control FITC |
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| 1F-692-C025 | ExBio | 0.025 mg | EUR 129.6 |
Mouse IgG2b Isotype Control FITC |
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| 1F-692-C100 | ExBio | 0.1 mg | EUR 212.4 |
Mouse IgG2a Isotype Control FITC |
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| 1F-724-C025 | ExBio | 0.025 mg | EUR 129.6 |
Ekspresija alfa, pi i mu GST-a u svakom uzorku tumora bila je u suprotnosti s in vitro osjetljivošću tumorskih stanica na doksorubicin, što je odlučeno inhibicijom lijeka unosa [Se-75] selenometionina odgovarajućim tumorskim stanicama u tradiciji. Ekspresija pi GST bila je povezana s rezistencijom tumorskih stanica na doksorubicin. Stupanj alfa, pi i mu GST nije bio povezan s preživljavanjem zahvaćene osobe.
